Original Research Paper
HISTOMORPHOLOGICAL SPECTRUM OF MALIGNANT LYMPHOMA IN TERTIARY CARE CENTRE IN HADOTI REGION
BACKGROUND:In hadoti region, we had analyzed all malignant lymphomas with aspect of age, sex, site, clinical features and type according to WHO classifications. This study aims to analyze histomorphological spectrum of lymphomas in a tertiary care center in hadoti region.MATERIAL AND METHODS:56 Lymphoid neoplasms of all age group diagnosed within 5 years from January 2012 to December 2016 in tertiary care centre, hadoti region, were analyzed. Clinical history, physical examination and available laboratory investigation were evaluated. The final diagnosis was based on histology according to WHO classification 2008 and four cases were confirmed with immunohistochemistry. RESULTS:Out of 56 cases of lymphoma, 66.1% (37 cases) were diagnosed as Non-Hodgkin lymphoma and 33.9% (19 cases) as Hodgkin disease, with an overall male predominance. Lymphadenopathy was the commonest presenting features in both the types of Lymphomas. On histopathology, majority of Non-Hodgkin lymphomas, 13 cases (35.13%) showed a diffuse pattern, while nodular sclerosis was the commonest type seen in Hodgkin disease 7 cases (36.8%).CONCLUSION:Non-Hodgkin lymphomas are two times more common than Hodgkin lymphoma. Patient presenting with lymphadenopathy with systemic features of lymphoma should be concerned and full work up should be done with presenting symptoms, physical examination, complete laboratory investigation and histopathological examination.
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