Original Research Paper

Unusual Histopathological Findings And Malignant Transformation In Mature Cystic Teratomas Of Ovary: A 2 Year Study With Review Of Literature

  Abstract :

Background- Mature cystic teratoma is a benign most common tumor of the ovary occurring mostly in young and middle aged females. In this paper, we report and review 18 cases of mature cystic teratomas received in Department Of Pathology over a 2 year period with malignant transformation in 2 cases, which makes it very important for pathologist to thoroughly examine the entire specimen of mature cystic teratomas.Material and Methods- Eighteen reported cases of mature cystic teratomas received in Deptt. Of Pathology, BPS GMC Khanpur Kalan, Sonepat over a 2 year period from November, 2019 to October, 2021 were studied and reviewed retrospectively. Data regarding age, size, laterality, gross, morphological features and surgery performed was retrieved from pathological archives. Results-In our study, most common age of presentation was 30-40 year age group. Most common presenting complaint was fullness in abdomen or abdominal distension. Four out of 18 cases studied i.e. 22.2% cases presented with bilateral ovarian cysts. Tumor size ranged from 6 to 20 cm in diameter. Seven cases i.e. 38.9% cysts were greater than or equal to 10 cm in diameter. 2 cases (11.11%) showed malignant transformation. Conclusion- It is very important to thoroughly examine the contralateral ovary to rule out bilateral presentation. Furthermost thorough examination is advised in older females, in tumors of size >10 cm and in tumors with solid areas to rule out any malignant transformation.

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