Original Research Paper

New Research and Development of Influenza Virus

  Abstract :

Influenza viruses are noteworthy human respiratory pathogens that cause equally seasonal, endemic infections and periodic, unpredictable pandemics. The worst pandemic on record, in 1918, killed approximately 50 million people worldwide. Human infections caused by H5N1 highly pathogenic avian influenza viruses have raised concern about the emergence of another pandemic. Timely and perfect identification of influenza virus is very critical for the disease diagnosis, outbreak management and outpatient management, to avoid incongruous use of antibiotics, virus surveillance and initiation of antiviral therapy in patients with high risk of complications. Swine origin influenza virus A (H1N1) recent pandemic and highly pathogenic avian influenza A virus (H5N1) circulation highlighted the need of rapid and accurate diagnosis of influenza virus and its sub types. Technical advances in the last period have made it possible to investigate influenza virus infection from the cellular and subcellular level to intact animals and humans. As a result, we have expanded a new understanding of the virus and disease. This review deliberates different approaches for measuring the amount of influenza virus particles in the air and assessing their infectiousness. Here we also discuss the data describing the association between the influenza virus subtypes and virus air transmission, and distribution of viral particles in aerosol drops of different sizes. COVID-19, also referred to as CORONAVIRUS, is a respiratory illness that was first detected in the Hubei province city of Wuhan, China, in late December 2019(WHO).

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