Original Research Paper
Cytomorphological spectrum of lymph node lesions on FNAC in a Tertiary Care Hospital-A retrospective study of 530 cases.
Introduction:Lymphadenopathy is one of the most commonly encountered clinical problem with etiologies varying from non-neoplastic to neoplastic conditions like inflammation,infection, primary or metastatic tumors. Materials and methods:This study was carried out in Department of Pathology at a Tertiary Care Centre from Nov. 2017 to Oct. 2018 to study the various cytomorphological features of neoplastic and nonneoplastic lesions of lymph nodes by FNAC in patients presenting with lymphadenopathy. Results: A total of 530 aspirates were obtained out of which 295 were males and 235 females. The age of the patients varied from 1 year to 81 years with a mean age of 41.5 years. A male to female ratio of 1.25:1 was noted. The most common group of lymph nodes aspirated were cervical (52.80%). A cytological diagnosis was made in 516 cases while no opinion was possible in 14 cases due to the inadequacy of the aspirates. Of the 516 cases, 199 cases (38.56%) were diagnosed as reactive hyperplasia, followed by 158 cases (30.62%) of tubercular lymphadenitis and 101 cases of metastatic malignancy i.e., 19.57%, 23 cases (4.46%) of acute suppurative lymphadenitis and 28 cases (5.43%) of nonHodgkins lymphoma (NHL) and 5 cases (0.97%)of Hodgkins lymphoma , 1 case (0.19%) of Rosai Dorfmans Disease and 1 case (0.19%) of cryptococcal lymphadenitis. Conclusion: The most common cause for enlarged lymph nodes were reactive lymphadenopathy followed by tuberculous lymphadenitis
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