Original Research Paper
A clinical study of neonatal sepsis in term & pretermwith reference to c-reactive protein.
INTRODUCTION:-Neonatal sepsis is a prominent cause of death during the neonatalperiod. newborn sepsis is a leading cause of newborn morbidity andmortality worldwide. Developing countries account for more than 95% ofinfant deaths between the ages of 0 and 2 months. Creactive protein(CRP) is one of the most studied and widely used laboratory tests forneonatal sepsis. C-reactive protein is essential in the immune responseto bacterial invasion. Its limited sensitivity during the early stages ofdisease is due to the delay in synthesis during the inflammatory responsMETHOD:-During the period of October 2020 to September 2022, all neonates with suspectedneonatal sepsis delivered in ANMMC Hospital and outside ANMMC Hospital wereincluded in the study.OUTCOME: One hundred neonates were suspected of having neonatal septicemia.There were 16 occurrences of inborn babies and 84 cases of outborn babies. Birthweight, gestational age, mother's febrile sickness, and more than three viginalexaminations.Conclusion: CRP has a high negative predictive value of 96-100% and can beutilised as a diagnostic of newborn sepsis to shorten antibiotic duration.During the period of October 2020 to September 2022, all neonates with suspected neonatalsepsis delivered in ANMMC Hospital and outside ANMMC Hospital were included in thestudy.Conclusion: CRP has a high negative predictive value of 96-100% and can be utilised as adiagnostic of newborn sepsis to shorten antibiotic duration.
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