Original Research Paper
Comparative Study Of Immune Activation And Inflammatory Markers Il-6 And Il-4 In Hiv Patients
HIV (Human Immunodeficiency virus) is indeed a retrovirus. Being a causative agent, it weakens the immunity that can leads to AIDS (Acquired Immune Deficiency Syndrome). The aim of the study is to evaluate the level of inflammatory markers (IL-6 and IL-4) in HIV+ patients. It was an observational case control study, carried out in Department of Biochemistry and Department of General Medicine (ART Unit), Sardar Patel Medical College, Bikaner and Rajasthan. Total 50 HIV+ patients and 50 healthy controls were taken. In this study, analysis of serum interleukins (IL-6 and IL-4) was done. Serum pro-inflammatory cytokines interleukin-6 and anti-inflammatory cytokines interleukin-4 level was markedly high in newly diagnosed HIV+ ART nave patients compared to follow-up patients who had taken 1-year ART treatment (p
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