Original Research Paper

Comprehensive Overview of SMARCA4-Deficient Thoracic Neoplasms

Dave Rushang M, Goswami Parth R, Parsana Riddhi R, Gajera Hiren M

  Abstract :

SMARCA4, a crucial component of the SWI/SNF chromatin remodeling complex, has recently been identified as a significant player in the pathogenesis of certain thoracic tumors. SMARCA4-deficient thoracic tumors represent a unique subset of cancers, characterized by the loss of SMARCA4 protein expression, which has been observed to correlate with aggressive clinical behavior and a distinct histopathological profile. This review aims to provide a comprehensive overview of SMARCA4-deficient thoracic tumors, offering insights into potential pathways for targeted interventions and improved patient outcomes.

  Keywords :

thoracic  

  Cite This Article:

COMPREHENSIVE OVERVIEW OF SMARCA4-DEFICIENT THORACIC NEOPLASMS, Dave Rushang M, Goswami Parth R, Parsana Riddhi R, Gajera Hiren M, INTERNATIONAL JOURNAL OF RESEARCH PATHOLOGY AND MICROBIOLOGY : Volume-8 | Issue-2 | April-2024

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