Research Paper
Epidemiological and Clinical profiles of Melioidosis in tertiary care centre in Northern Sri Lanka.
Melioidosis is sporadically reported from various parts of Sri Lanka. It is major recent endemic in Northern Sri Lanla. It is caused by Burkholderia pseudomallei, a Gram-negative, oxidase positive bacillus. The first case of melioidosis was reported in a European tea broker in 1927 in Sri Lanka. We present a case series of seven patients of culture or serologically proven melioidosis from Northern Sri Lanka, highlighting the different clinical manifestations of the disease .Melioidosis had a varied presentation involving multiple abscesses in the skin, liver, spleen, mediastinum and septic arthritis. It presented as either an acute fulminant septicaemia with a high mortality to a chronic localized infection. Most cases had predisposing risk factors such as diabetes and occupational risk.
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