Original Research Paper
A CLINICAL, BACTERIOLOGICAL AND MYCOLOGICAL PROFILE AMONG PATIENTS WITH CHRONIC SUPPURATIVE OTITIS MEDIA IN A TERTIARY CARE HOSPITAL
Background and Objectives: Chronic suppurative otitis media (CSOM) is defined as a perforation of the tympanic membrane, which has been prevented from healing by chronic inflammation and has persisted for more than 3 months, with a history of discharge for atleast 6 weeks. It is the most commonly encountered disease in otolaryngology practice. Due to advent of newer and sophisticated antibiotics, microbial flora is changing constantly. Culture of the middle ear fluid constitute a valuable tool for definitive diagnosis, to guide therapy, to evaluate treatment failures and for research studies to determine the efficacy of antimicrobials against the most common agents. Many studies have been done on aerobic bacteria and fungal isolates causing CSOM but very few studies are done on anaerobic bacteria causing CSOM. Hence, the present study will be undertaken to know the microbiological profile of CSOM including anaerobes. Objectives of the study:(1) To estimate the prevalence of bacterial (aerobic and anaerobic) and mycotic flora in middle ear infection among clinically diagnosed chronic suppurative otitis media patients.(2)To assess the antibiotic sensitivity pattern of the aerobic bacterial isolates. Methods:Hundred clnically diagnosed cases of CSOM of all age groups and both the sexes attending the ENT OPD with either unilateral or bilateral ear discharge were considered in this study.Following a detailed questionnaire, four ear swabs were taken from each patients and processed in Microbiology laboratory. Aerobic and anaerobic bacterial and fungal isolates were identified and corresponding antimicrobial sensitivity tests were done for aerobic bacterial isolates based on standard methods.Results :Among the aerobic bacterial isolates Pseudomonas aeruginosa (40%) was the most predominant bacteria isolated followed by Staphylococcus aureus (21%).The most common anaerobic bacteria was Finegoldia magna(25%) followed by Fusobacterium necrophorum(18.75%). Aspergillus niger (35%)was the most predominant fungus followed by Candida albicans(25%). Gram positive cocci were highly sensitive to Vancomycin, Teicoplanin, Tetracycline.Gram negative bacilli belongs to Enterobacteriacae family were highly sensitive to Ciprofloxacin and Cefepime.Gram negative non fermenters were highly sensitive to Amikacin, Ticarcillin Clavulinic acid .Conclusion:Due to emergence of multidrug resistant organisms appropriate antibiotics should be selected before starting treatment.
CSOM Aerobic anaerobic isolates and fungal isolates Pseudomonas aeruginosa Finegoldia magna Aspergillus niger Vancomycin Amikacin
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